One of the criticisms of almost any gambling strategy is that it requires you to play 'perfectly', and that this is not realistic of a human.  There is some truth to this.  For sure, the theoretical payback can only be achieved if you play the strategy perfectly.  Sometimes, the strategies are present are not 'perfect'.  They have already been altered to give a human a reasonable chance to play the strategy presented perfectly.  For example, in the game of Ultimate Texas Hold'em, the strategy for the 2x Wager consists of about 10 or 12 'rules'.  This can already prove challenging for a human.  If a complete computer perfect strategy were presented, it would likely have hundreds of rules.  No human, short of Rain Man, would be able to play this even close to perfect.